Luteinizing hormone-releasing hormone in thymus and hypothalamus of rat fetuses: suppressing effect of antagonist and of antibodies on concanavalin A-induced proliferation of thymocytes.

@article{Zakharova2000LuteinizingHH,
  title={Luteinizing hormone-releasing hormone in thymus and hypothalamus of rat fetuses: suppressing effect of antagonist and of antibodies on concanavalin A-induced proliferation of thymocytes.},
  author={Ludmila A Zakharova and Irina V Malyukova and Elena I Adamskaya and Tatyana A. Kuznetsova and Irina Shishkina},
  journal={Biochemistry. Biokhimiia},
  year={2000},
  volume={65 10},
  pages={1135-9}
}
The effect of endogenous luteinizing hormone-releasing hormone (LHRH) on the proliferation induced by concanavalin A (Con A) in rat fetal thymocytes was studied. A selective antagonist (2 microg per fetus) or antibodies to LHRH (20 microl per fetus) were injected in utero into 20-day-old rat fetuses, and this resulted in a two- or fivefold decrease in the… CONTINUE READING