Luteinizing hormone receptors and testosterone synthesis in two distinct populations of Leydig cells.

@article{Payne1980LuteinizingHR,
  title={Luteinizing hormone receptors and testosterone synthesis in two distinct populations of Leydig cells.},
  author={Anita H. Payne and James R. Downing and Ka Leung Wong},
  journal={Endocrinology},
  year={1980},
  volume={106 5},
  pages={1424-9}
}
Dispersed cells from whole testes or from isolated interstitial tissue of mature rats, yielded two distinct populations of Leydig cells when subjected to centrifugation in a 0-40% metrizamide gradient. One population (I) was found in a fractions with a density of 1.085-1.117 g/cm3, and the other population (II) was found in fractions with a density of 1.128-1.145 g/cm3. Binding of 125I-labeled hCG by each population of cells indicated a single class of binding sites with the same high binding… CONTINUE READING
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