Luteinising hormone secretion from the perifused ovine pars tuberalis and pars distalis: effects of gonadotropin-releasing hormone and melatonin.

@article{Skinner1997LuteinisingHS,
  title={Luteinising hormone secretion from the perifused ovine pars tuberalis and pars distalis: effects of gonadotropin-releasing hormone and melatonin.},
  author={Donal C. Skinner and Jane Elizabeth Robinson},
  journal={Neuroendocrinology},
  year={1997},
  volume={66 4},
  pages={263-70}
}
It is not known where melatonin acts to influence the neuroendocrine axis of seasonally breeding mammals. However, since the pars tuberalis (PT) contains the highest density of melatonin receptors, this adenohypophyseal subdivision is a potential target. Gonadotropes are the only immunocytochemically detectable adenohypophyseal cell type of abundance in the PT. This study investigated whether melatonin could modulate basal and/or gonadotropin-releasing hormone (GnRH)-stimulated luteinising… CONTINUE READING