Lurasidone in the treatment of bipolar depression with mixed (subsyndromal hypomanic) features: post hoc analysis of a randomized placebo-controlled trial.

@article{McIntyre2015LurasidoneIT,
  title={Lurasidone in the treatment of bipolar depression with mixed (subsyndromal hypomanic) features: post hoc analysis of a randomized placebo-controlled trial.},
  author={Roger S. McIntyre and Josephine B. Cucchiaro and Andrei A. Pikalov and Hans Kroger and Antony D. Loebel},
  journal={The Journal of clinical psychiatry},
  year={2015},
  volume={76 4},
  pages={398-405}
}
OBJECTIVE Mixed (subsyndromal hypomanic) features are prevalent in patients with bipolar depression and are associated with more severe and complex illness, including increased risk for suicide attempts, higher switch to mania during antidepressant therapy, and a higher rate of recurrence. The aim of this post hoc analysis was to evaluate the efficacy and safety of lurasidone in the treatment of patients with bipolar depression presenting with mixed features. METHOD Patients with a DSM-IV-TR… CONTINUE READING
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