Lung surfactant as a drug delivery system.

@article{Vermehren2006LungSA,
  title={Lung surfactant as a drug delivery system.},
  author={Charlotte Vermehren and Sven Frokjaer and Tore Aurstad and Jens Kielsgaard Hansen},
  journal={International journal of pharmaceutics},
  year={2006},
  volume={307 1},
  pages={
          89-92
        }
}
Lung surfactant is a complex mixture of mainly phospholipids and proteins. The composition leads to a unique spreading effect of the surfactant as well as spontaneous vesicle formation, which may be favourable characteristics of a drug delivery system for pulmonary delivery. The aim of study was to investigate the potential use of the surfactant extract, HL10 (LeoPharma, DK) as a drug delivery system. Studies involved incorporation of hydrophilic- and amphipathic model drugs (sucrose and… CONTINUE READING
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