Lung stress and strain during mechanical ventilation: any difference between statics and dynamics?

@article{Protti2013LungSA,
  title={Lung stress and strain during mechanical ventilation: any difference between statics and dynamics?},
  author={Alessandro Protti and Davide Tommaso Andreis and Massimo Monti and Alessandro Santini and Cristina Carin Sparacino and Thomas Langer and Emiliano Votta and Stefano Gatti and Luciano Burgos Lombardi and Orazio Leopardi and Serge Masson and Massimo Cressoni and Luciano Gattinoni},
  journal={Critical care medicine},
  year={2013},
  volume={41 4},
  pages={1046-55}
}
OBJECTIVE Tidal volume (VT) and volume of gas caused by positive end-expiratory pressure (VPEEP) generate dynamic and static lung strains, respectively. Our aim was to clarify whether different combinations of dynamic and static strains, resulting in the same large global strain, constantly produce lung edema. DESIGN Laboratory investigation. SETTING Animal unit. SUBJECTS Twenty-eight healthy pigs. INTERVENTIONS After lung computed tomography, 20 animals were ventilated for 54 hours at… CONTINUE READING
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