Lung reflexes in rabbits during pulmonary stretch receptor block by sulphur dioxide.

@article{Davies1978LungRI,
  title={Lung reflexes in rabbits during pulmonary stretch receptor block by sulphur dioxide.},
  author={A. C. Davies and Michael Dixon and David Callanan and Andrew Huszczuk and John G Widdicombe and J. C. M. Wise},
  journal={Respiration physiology},
  year={1978},
  volume={34 1},
  pages={83-101}
}
Anaesthetized rabbits were given 200 ppm sulphur dioxide to breathe for 10 min. This abolished activity in 23 of 26 pulmonary stretch receptors, while leaving that of lung irritant receptors unimpaired. The Breuer-Hering reflex was abolished and breathing became deeper and slower. Inspiratory time (tI) was increased and expiratory time (tE) decreased. Subsequent vagotomy increased tidal volume (VT), tI and tE. In animals with stretch receptors blocked, injections of phenyl diguanide and… CONTINUE READING
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