Lung perfusion, shunt fraction, and oxygenation during one-lung ventilation in pigs: the effects of desflurane, isoflurane, and propofol.

@article{Schwarzkopf2003LungPS,
  title={Lung perfusion, shunt fraction, and oxygenation during one-lung ventilation in pigs: the effects of desflurane, isoflurane, and propofol.},
  author={Konrad R G Schwarzkopf and Torsten Schreiber and N P Preussler and Elke Gaser and Lars Hueter and Reinhard Bauer and Harald Schubert and Waheedullah Karzai},
  journal={Journal of cardiothoracic and vascular anesthesia},
  year={2003},
  volume={17 1},
  pages={
          73-5
        }
}
OBJECTIVE To study how desflurane, isoflurane, and propofol affect pulmonary perfusion, shunt fraction, and systemic oxygenation during one-lung ventilation (OLV) in vivo. DESIGN Prospective animal study with a crossover design. SETTING Animal laboratory of a university hospital. PARTICIPANTS Twelve female pigs. INTERVENTIONS The pigs were anesthetized, tracheally intubated, and mechanically ventilated. After placement of femoral arterial and thermodilution pulmonary artery catheters, a… CONTINUE READING
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