Lung morphometry using hyperpolarized 129 Xe multi-b diffusion MRI with compressed sensing in healthy subjects and patients with COPD.

@article{Zhang2018LungMU,
  title={Lung morphometry using hyperpolarized 129 Xe multi-b diffusion MRI with compressed sensing in healthy subjects and patients with COPD.},
  author={Huiting Zhang and Junshuai Xie and Sa Xiao and Xiuchao Zhao and Ming Zhang and Lei Shi and Ke Wang and Guangyao Wu and Xianping Sun and Chaohui Ye and Xin Zhou},
  journal={Medical physics},
  year={2018},
  volume={45 7},
  pages={
          3097-3108
        }
}
PURPOSE To demonstrate the feasibility of compressed sensing (CS) to accelerate the acquisition of hyperpolarized (HP) 129 Xe multi-b diffusion MRI for quantitative assessments of lung microstructural morphometry. METHODS Six healthy subjects and six chronic obstructive pulmonary disease (COPD) subjects underwent HP 129 Xe multi-b diffusion MRI (b = 0, 10, 20, 30, and 40 s/cm2 ). First, a fully sampled (FS) acquisition of HP 129 Xe multi-b diffusion MRI was conducted in one healthy subject… CONTINUE READING
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