Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity.

@article{Alvarez2008LungME,
  title={Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity.},
  author={Diego F. Alvarez and Lan Huang and Judy A. C. King and Mohammed Khair Elzarrad and Mervin C. Yoder and Troy Stevens},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2008},
  volume={294 3},
  pages={L419-30}
}
Endothelial progenitor cells (EPCs) have been isolated postnatally from bone marrow, blood, and both the intima and adventitia of conduit vessels. However, it is unknown whether EPCs can be isolated from the lung microcirculation. Thus we sought to determine whether the microvasculature possesses EPCs capable of de novo vasculogenesis. Rat pulmonary artery (PAEC) and microvascular (PMVEC) endothelial cells were isolated and selected by using a single-cell clonogenic assay. Whereas the majority… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 63 extracted citations

Functional and molecular heterogeneity of pulmonary endothelial cells.

Proceedings of the American Thoracic Society • 2011
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Clustering of replicating cells in aortic endothelium.

Proceedings of the National Academy of Sciences of the United States of America • 1976
View 3 Excerpts
Highly Influenced

Proproliferative phenotype of pulmonary microvascular endothelial cells.

American journal of physiology. Lung cellular and molecular physiology • 2007
View 1 Excerpt

Similar Papers

Loading similar papers…