Lung ischemia-reperfusion injury in awake sheep: protection with verapamil.

@article{Wickersham1991LungII,
  title={Lung ischemia-reperfusion injury in awake sheep: protection with verapamil.},
  author={N E Wickersham and Jeffrey J. Johnson and Barbara O. Meyrick and Rene Gilroy and James E Loyd},
  journal={Journal of applied physiology},
  year={1991},
  volume={71 4},
  pages={1554-62}
}
We caused unilateral lung ischemia-reperfusion injury in awake sheep by simultaneously occluding the left pulmonary artery and left main stem bronchus for 12 h. The occluded left lung was inflated with nitrogen. Reperfusion resulted in an elevation of lung lymph flow from 1.3 to 5.0 ml/15 min and an increase in lymph-to-plsma protein concentration ratios… CONTINUE READING