Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process.

@article{Hengst2010LungII,
  title={Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process.},
  author={Willem A den Hengst and Jan F Gielis and Judy Y Lin and Paul E Van Schil and Leon de Windt and An L Moens},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2010},
  volume={299 5},
  pages={H1283-99}
}
Lung ischemia-reperfusion injury remains one of the major complications after cardiac bypass surgery and lung transplantation. Due to its dual blood supply system and the availability of oxygen from alveolar ventilation, the pathogenetic mechanisms of ischemia-reperfusion injury in the lungs are more complicated than in other organs, where loss of blood flow automatically leads to hypoxia. In this review, an extensive overview is given of the molecular and cellular mechanisms that are involved… CONTINUE READING

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