Lung involvement in systemic sclerosis (scleroderma): relation to classification based on extent of skin involvement or autoantibody status.

@article{Kane1996LungII,
  title={Lung involvement in systemic sclerosis (scleroderma): relation to classification based on extent of skin involvement or autoantibody status.},
  author={Gregory C. Kane and John Varga and Emily F. Conant and Paul W Spirn and Sergio A Jimenez and James E. Fish},
  journal={Respiratory medicine},
  year={1996},
  volume={90 4},
  pages={223-30}
}
Lung involvement accounts for significant morbidity and is a leading cause of mortality in patients with systemic sclerosis (SSc). It has been shown that different patterns of pulmonary involvement are seen in different subtypes of SSc. This paper reports a retrospective review of 72 patients with SSc to determine whether disease classification according to the extent of skin involvement alone (diffuse vs. limited) or autoantibody status was predictive of pulmonary parenchymal involvement. The… CONTINUE READING