Lung injury induced by secondhand smoke exposure detected with hyperpolarized helium-3 diffusion MR.

@article{Wang2014LungII,
  title={Lung injury induced by secondhand smoke exposure detected with hyperpolarized helium-3 diffusion MR.},
  author={Chengbo Wang and John P. Mugler and Eduard E de Lange and James T. Patrie and J. F. Mata and Talissa A. Altes},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2014},
  volume={39 1},
  pages={77-84}
}
PURPOSE To determine whether helium-3 diffusion MR can detect the changes in the lungs of healthy nonsmoking individuals who were regularly exposed to secondhand smoke. MATERIALS AND METHODS Three groups were studied (age: 59 ± 9 years): 23 smokers, 37 exposure-to-secondhand-smoke subjects, and 29 control subjects. We measured helium-3 diffusion values at diffusion times from 0.23 to 1.97 s. RESULTS One-way analysis of variance revealed that the mean area under the helium-3 diffusion curves… CONTINUE READING