Lung inflammatory response in pneumonia.

  title={Lung inflammatory response in pneumonia.},
  author={Concepci{\'o}n Mont{\'o}n and Antoni Torres},
  journal={Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace},
  volume={53 1},
In normal conditions, alveolar macrophages (AMs) are the main cells that respond to bacteria that reach lower airways. However, if the microbial inoculum is too high or too virulent to be stopped by AM alone, these cells recruit polymorphonuclear neutrophils (PMN) into the alveoli from the vascular compartment. Cytokines, such as tumour necrosis factor-alpha (TNF-alpha), interleukin-1-beta (IL-beta), interleukin-6 (IL-6), and interleukin-8 (IL-8), secreted by the AM are able to attract PMN… CONTINUE READING
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