Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

Abstract

The toxic and inflammatory potential of 5 different types of nanoparticles were studied in a sensitive model for pulmonary effects in apolipoprotein E knockout mice (ApoE-/-). We studied the effects instillation or inhalation Printex 90 of carbon black (CB) and compared CB instillation in ApoE-/- and C57 mice. Three and 24 h after pulmonary exposure… (More)
DOI: 10.1186/1743-8977-6-2

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