Lung hyaluronan decreases during group B streptococcal pneumonia in neonatal piglets.

@article{Juul1996LungHD,
  title={Lung hyaluronan decreases during group B streptococcal pneumonia in neonatal piglets.},
  author={Sandra E Juul and Michael G. Kinsella and William E. Truog and Ronald L. Gibson and Gregory J. Redding},
  journal={American journal of respiratory and critical care medicine},
  year={1996},
  volume={153 5},
  pages={
          1567-70
        }
}
Neonatal Group B streptococcus (GBS) sepsis and pneumonia result in lung injury and remain a major cause of morbidity and mortality in the newborn. Increased lung hyaluronan (HA) content is an important component of the lung's early response to damage in diseases such as adult respiratory distress syndrome (ARDS), infant respiratory distress syndrome (IRDS), and bleomycin-induced fibrosis. It is known, however, that GBS virulence factors include specific secretory enzymes such as hyaluronidase… CONTINUE READING