Lung function in children following repair of tracheoesophageal fistula.

@article{Milligan1979LungFI,
  title={Lung function in children following repair of tracheoesophageal fistula.},
  author={Don W Milligan and Henry Levison},
  journal={The Journal of pediatrics},
  year={1979},
  volume={95 1},
  pages={
          24-7
        }
}
Lung function and bronchial reactivity by methacholine challenge were studied in 24 patients seven to 18 years after repair of type I tracheoesophageal fistula. Only one patient had no abnormalities of the variables tested. Thirteen patients had obstructive airways disease, five had a restrictive defect, and 15 had a positive methacholine challenge. It is postulated that continuing subclinical aspiration of esophageal contents causes lung damage and renders the airways hyperreactive. 

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