Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation.

Abstract

Development of fibrosis involves an increase in the deposition of connective tissue components including collagens, fibronectin and proteoglycans. One hypothesis to account for matrix deposition in fibrosis is that fibroblast with differing matrix producing capacity are involved in the fibrotic process. To test this hypothesis, primary fibroblast cultures… (More)

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@article{WestergrenThorsson2004LungFC, title={Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation.}, author={Gunilla Westergren-Thorsson and Patricia Sime and Manel Jordana and Jack Gauldie and Bengt S{\"a}rnstrand and Anders Malmstr{\"o}m}, journal={The international journal of biochemistry & cell biology}, year={2004}, volume={36 8}, pages={1573-84} }