Lung disease, T-cells and inflammation in common variable immunodeficiency disorders.

@article{Gregersen2013LungDT,
  title={Lung disease, T-cells and inflammation in common variable immunodeficiency disorders.},
  author={Stina Gregersen and Are Martin Holm and B\orre Fevang and Thor Ueland and Liv I B Sikkeland and Trond Mogens Aal\okken and Georg Karl Mynarek and Johny Steinar Kongerud and P{\aa}l Aukrust and Bj\orn Johansen and Stig Sophus Fr\oland},
  journal={Scandinavian journal of clinical and laboratory investigation},
  year={2013},
  volume={73 6},
  pages={514-22}
}
INTRODUCTION Besides hypogammaglobulinemia and recurrent infections, abnormalities of T-cells might contribute to lung damage in common variable immunodeficiency disorders (CVID). MATERIALS AND METHODS In 16 adult patients, the majority of whom had pulmonary abnormalities, we studied T-cell subsets and markers of inflammation in bronchoalveolar lavage fluid (BALF) and blood and their relations with pulmonary function and high resolution computed tomography (HRCT). RESULTS We demonstrated… CONTINUE READING