Lung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devices.

@article{Newman1998LungDO,
  title={Lung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devices.},
  author={Stephen P. Newman and Jeffrey Brown and Karen P Steed and Sandie J Reader and H Kladders},
  journal={Chest},
  year={1998},
  volume={113 4},
  pages={957-63}
}
STUDY OBJECTIVES To compare lung deposition of fenoterol or flunisolide administered from a novel, multidose inhalation device delivering liquid droplets (RESPIMAT; Boehringer Ingelheim Ltd; Bracknell, UK) or from conventional metered-dose inhalers (MDIs) with and without spacers. DESIGN Two randomized, three-way crossover studies. SETTING Clinical research laboratory. PARTICIPANTS Healthy, nonsmoking volunteers. INTERVENTIONS In one study, radiolabeled aerosols of fenoterol from the… CONTINUE READING
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