Lung cancer pathogenesis associated with wood smoke exposure.

  title={Lung cancer pathogenesis associated with wood smoke exposure.},
  author={Javier D{\'i}es Delgado and Luis Enrique Mart{\'i}nez Mart{\'i}nez and Therasa T S{\'a}nchez and Alejandra E Ram{\'i}rez and Cecilia Iturria and Georgina Gonz{\'a}lez-{\'A}vila},
  volume={128 1},
BACKGROUND Tobacco is considered the most important cause of lung cancer, but other factors could also be involved in its pathogenesis. The aim of the present work was to establish an association between wood smoke exposure and lung cancer pathogenesis, and to analyze the effects of wood smoke on p53 and murine double minute 2 (MDM2) protein expression. DESIGN Blood samples were obtained from 62 lung cancer patients, 9 COPD patients, and 9 control subjects. Of the 62 lung cancer patients, 23… CONTINUE READING
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