Lung bioengineering: advances and challenges in lung decellularization and recellularization

@article{Uriarte2018LungBA,
  title={Lung bioengineering: advances and challenges in lung decellularization and recellularization},
  author={Juan J. Uriarte and Franziska E. Uhl and Sara Rolandsson Enes and Robert A. Pouliot and Daniel J. Weiss},
  journal={Current Opinion in Organ Transplantation},
  year={2018},
  volume={23},
  pages={673–678}
}
Purpose of review Bioengineering the lung based on its natural extracellular matrix (ECM) offers novel opportunities to overcome the shortage of donors, to reduce chronic allograft rejections, and to improve the median survival rate of transplanted patients. During the last decade, lung tissue engineering has advanced rapidly to combine scaffolds, cells, and biologically active molecules into functional tissues to restore or improve the lung's main function, gas exchange. This review will… Expand
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