Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice

@article{Ashley2020LungAG,
  title={Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice},
  author={Shanna L. Ashley and Michael W. Sjoding and Antonia P. Popova and Tracy X. Cui and Matthew J. Hoostal and Thomas M. Schmidt and William R. Branton and Michael G. Dieterle and Nicole R. Falkowski and Jennifer M. Baker and Kevin J. Hinkle and Kristine E Konopka and John R. Erb-Downward and Gary B. Huffnagle and Robert P. Dickson},
  journal={Science Translational Medicine},
  year={2020},
  volume={12}
}
Inhaled oxygen alters the microbiota of mice and humans, which may contribute to oxygen-induced lung injury. Linking hyperoxia to microbial dysbiosis Inhaled oxygen is a commonly administered therapy that causes severe lung injury in animals and is associated with poor clinical outcomes in humans. The bacteria that live within the body’s lungs and gut are highly variable in their tolerance of oxygen. Ashley et al. now report that in both humans and mice, inhaled oxygen influenced respiratory… 
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