Lung Defenses: Intrinsic, Innate, and Adaptive

  title={Lung Defenses: Intrinsic, Innate, and Adaptive},
  author={Keely G. Smith and Ankur A Kamdar and James M Stark},
Abstract Pediatric pulmonologists are frequently consulted on the child with “too many” respiratory infections. Considering the volume of air, particulates, chemicals, and potential airborne pathogens inspired with each breath, the question should actually be “Why don't we get more infections?” The large surface area of the conducting airways and alveolar surfaces (>70 m 2 in the adult) that is available for these particles to deposit poses a great challenge for the lung defenses. The anatomy… CONTINUE READING