Lung Altered Expression of IL-1β mRNA and Its Signaling Pathway Molecules in Obese-asthmatic Male Wistar Rats.

@article{Aslani2016LungAE,
  title={Lung Altered Expression of IL-1β mRNA and Its Signaling Pathway Molecules in Obese-asthmatic Male Wistar Rats.},
  author={Mohammad Reza Aslani and Rana Keyhanmanesh and Amir Mehdi Khamaneh and Mohammad Ali Ebrahimi Saadatlou and Mehran Mesgari Abbasi and Mohammad Reza Alipour},
  journal={Iranian journal of allergy, asthma, and immunology},
  year={2016},
  volume={15 3},
  pages={
          183-97
        }
}
Epidemiological and clinical studies indicate a close relationship between obesity and asthma. Here, we determined the impact of diet-induced obesity on the expression levels of IL-1β, IRAK-1 and TRAF-6 mRNA as well as IL-1β protein level and pathological changes in male Wistar rat's lung after sensitization with ovalbumin (OVA). Twenty male Wistar rats divided into four groups, control with normal diet (C+ND), OVA-sensitized with normal diet (S+ND), control with high-fat diet (C+HFD), and OVA… CONTINUE READING
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Recent insight into obesity and asthma.

  • Current opinion in pulmonary medicine
  • 2010

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