Luminometric microplate hybridization for detection of varicella-zoster virus PCR product from cerebrospinal fluid.

@article{Koskiniemi1997LuminometricMH,
  title={Luminometric microplate hybridization for detection of varicella-zoster virus PCR product from cerebrospinal fluid.},
  author={Marjaleena Koskiniemi and Laura Mannonen and Arja Kallio and Antti Vaheri},
  journal={Journal of virological methods},
  year={1997},
  volume={63 1-2},
  pages={71-9}
}
We modified and optimized a new microplate hybridization assay to detect the varciella-zoster virus (VZV) PCR product, and studied cerebrospinal fluid (CSF) samples of 287 patients with meningitis, encephalitis or other neurological diseases or symptoms. Specific antibodies to VZV and reference antigens were determined by enzyme immunoassay from serum and CSF, they were then compared with clinical findings and with the results obtained by VZV-PCR using different detection methods for VZV… CONTINUE READING

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