Luminol as a probe to assess reactive oxygen species production from redox-cycling drugs in cultured hepatocytes.


The use of chemilumigenic probes to monitor the production of chemically induced reactive oxygen species in situ has been hampered by commonly occurring interference of test compounds with radical intermediates of the probe and by the lack of suitable on-line detection systems. In this study we have explored the ability of the cell-permeable agent luminal… (More)
DOI: 10.1080/15376510209167938