Luminance contrast of a visual stimulus modulates the BOLD response more than the cerebral blood flow response in the human brain

@article{Liang2013LuminanceCO,
  title={Luminance contrast of a visual stimulus modulates the BOLD response more than the cerebral blood flow response in the human brain},
  author={Christine L. Liang and Beau M. Ances and Joanna E. Perthen and Farshad Moradi and Joy Liau and Giedrius T. Buracas and Susan R. Hopkins and Richard B. Buxton},
  journal={NeuroImage},
  year={2013},
  volume={64},
  pages={104-111}
}
The blood oxygenation level dependent (BOLD) response measured with functional magnetic resonance imaging (fMRI) depends on the evoked changes in cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO(2)) in response to changes in neural activity. This response is strongly modulated by the CBF/CMRO(2) coupling relationship with activation, defined as n, the ratio of the fractional changes. The reliability of the BOLD signal as a quantitative reflection of underlying physiological… CONTINUE READING
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