Lumbar bone marrow microcirculation measurements from dynamic contrast-enhanced magnetic resonance imaging is a predictor of event-free survival in progressive multiple myeloma.

@article{Hillenga2007LumbarBM,
  title={Lumbar bone marrow microcirculation measurements from dynamic contrast-enhanced magnetic resonance imaging is a predictor of event-free survival in progressive multiple myeloma.},
  author={Jens Hillenga\ss and Klaus S Wasser and S. Delorme and Fabian Kiessling and Christian M. Zechmann and Axel Benner and Hans-Ulrich Kauczor and Anthony D. Ho and Hartmut Goldschmidt and Thomas M. Moehler},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2007},
  volume={13 2 Pt 1},
  pages={475-81}
}
PURPOSE Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with high temporal resolution enables the detection of microcirculation variables amplitude A and exchange rate constant k(ep). In this study, the prognostic value of the DCE-MRI variables for overall survival and event-free survival in patients with progressive multiple myeloma was investigated. EXPERIMENTAL DESIGN Between 1999 and 2001, 65 patients with progressive or relapse of multiple myeloma requiring therapy were… CONTINUE READING