Lumbar Puncture and Brain Herniation in Acute Bacterial Meningitis: A Review

  title={Lumbar Puncture and Brain Herniation in Acute Bacterial Meningitis: A Review},
  author={Ari R. Joffe},
  journal={Journal of Intensive Care Medicine},
  pages={194 - 207}
  • A. Joffe
  • Published 1 July 2007
  • Medicine
  • Journal of Intensive Care Medicine
There has been controversy regarding the risk of cerebral herniation caused by a lumbar puncture (LP) in acute bacterial meningitis (ABM). This review discusses in detail the issues involved in this controversy. Cerebral herniation occurs in about 5% of patients with ABM, accounting for about 30% of the mortality. In many reports, LP is temporally strongly associated with this event of herniation and is most likely causative based on pathophysiologic arguments. Although a computed tomography… 

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