Lucigenin chemiluminescence in the assessment of neutrophil superoxide production.

@article{Gyllenhammar1987LucigeninCI,
  title={Lucigenin chemiluminescence in the assessment of neutrophil superoxide production.},
  author={Hans Gyllenhammar},
  journal={Journal of immunological methods},
  year={1987},
  volume={97 2},
  pages={209-13}
}
Lucigenin-amplified chemiluminescence (LUCL) was induced by .O2- (from the xanthine/xanthine-oxidase reaction) but not, as with luminol-augmented CL (LCL), by myeloperoxidase (MPO) and only weakly by H2O2 or the H2O2-MPO-Cl- system. Neutrophil LUCL induced by fMet-Leu-Phe (fMLP) was dose-dependently inhibited by scavengers of .O2- but not by NaN3, catalase, mannitol or taurine. Response patterns of several soluble stimuli (leukotriene B4 (LTB4), platelet-activating factor (PAF), fMLP, A23187… CONTINUE READING

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