Lucidimine A-D, four new alkaloids from the fruiting bodies of Ganoderma lucidum

@article{Zhao2015LucidimineAF,
  title={Lucidimine A-D, four new alkaloids from the fruiting bodies of Ganoderma lucidum},
  author={Zhen-Zhu Zhao and Heping Chen and Tao Feng and Zheng-Hui Li and Zejun Dong and Jikai Liu},
  journal={Journal of Asian Natural Products Research},
  year={2015},
  volume={17},
  pages={1160 - 1165}
}
Abstract Four new polycylic alkaloids, lucidimine A–D, were isolated from the fruiting bodies of Ganoderma lucidum. Their chemical structures were established based on 1D and 2D NMR data as well as HREIMS/HRESIMS analyses. 
20 Citations
A new nortriterpenoid and an ergostane-type steroid from the fruiting bodies of the fungus Ganoderma resinaceum
TLDR
One new expoxy nortriterpenoid and one new ergostane-type steroid were obtained from the fruiting bodies of the fungus Ganoderma resinaceum and the known compounds were identified by comparing spectroscopic data with those reported in literature.
Chromone Alkaloids: Structural Features, Distribution in Nature, and Biological Activity
Structural data of chromone alkaloids and antibiotics related to them that were isolated from natural sources up to 2017 are systematized in this review. Information on their biological activity is
Total Syntheses and Biological Evaluation of the Ganoderma lucidum Alkaloids Lucidimines B and C
TLDR
It is demonstrated, for the first time, that the alkaloidal constituents derived from G. lucidum are biologically active and may, therefore, contribute to the beneficial health claims made for this nutraceutical.
Connection of Ganoderma Lucidum with Health
TLDR
Clinical and pharmacological studies showed that G. lucidum is composed of hundreds of bioactive components with immunomodulatory, antioxidant, antiaging, antiviral, Connection of Ganoderma Lucidum with Health.
Meroterpenoids With Protein Tyrosine Phosphatase 1B Inhibitory Activities From the Fruiting Bodies of Ganoderma ahmadii
TLDR
A chemical investigation of the fruiting bodies of Ganoderma ahmadii led to the isolation of seven new meroterpenoids, named ganoduriporols F-L (1–7), which represent the first examples of ganoderma-type meroter penoids bearing oxepane rings in their skeletons.
Two pairs of alkaloid enantiomers from Ganoderma luteomarginatum
Chemical Components of Ganoderma.
TLDR
The structural classifications and characteristics and separation methods were summarized and the components in Ganoderma contained triterpenes, meroterpenoids, steroids, alkaloids, nucleosides, nucleobases, and polysaccharides.
...
1
2
...

References

SHOWING 1-10 OF 17 REFERENCES
New alkaloids from the fruiting bodies of Ganoderma sinense
Four new alkaloids, sinensines B–E (1–4), together with one known alkaloid, sinensine (5), were isolated from the fruiting bodies of Ganoderma sinense. Their structures were elucidated on the basis
(±)-Sinensilactam A, a pair of rare hybrid metabolites with Smad3 phosphorylation inhibition from Ganoderma sinensis.
TLDR
(+)- and (-)-Sinensilactam A (1), novel hybrid metabolites possessing a unique 2H-pyrrolo[2,1-b][1,3]oxazin-6(7H)-one ring system, were isolated from the fruit bodies of Ganoderma sinensis and a plausible pathway for the biosynthesis of 1 is proposed.
Use of the oxazole-olefin diels-alder reaction in the total synthesis of the monoterpene alkaloids (-)-plectrodorine and (+)-oxerine.
TLDR
A full account of the total synthesis of two monoterpene alkaloids, (-)-plectrodorine [(-)-1] and (+)-oxerine [(+)-3], is presented and the absolute configuration of this alkaloid is not yet fully understood.
Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs
TLDR
Overall, Gl has potential to reduce LDL cholesterol in vivo through various mechanisms and next steps are to fully characterize bioactive components in lipid soluble/insoluble fractions and evaluate bioactivity of isolated fractions.
Effect of Ganoderma lucidum hydroalcoholic extract on insulin release in rat-isolated pancreatic islets
TLDR
The results demonstrate that G. lucidum acts directly on the Langerhans islets to increase basal insulin release.
Ganoderma lucidum (Reishi) Inhibits Cancer Cell Growth and Expression of Key Molecules in Inflammatory Breast Cancer
TLDR
The potential of the medicinal mushroom Ganoderma lucidum (Reishi) as an attractive candidate for anti-IBC therapy is described, and results show that Reishi selectively inhibits cancer cell viability although it does not affect the viability of noncancerous mammary epithelial cells.
Org
  • Lett. 17, 1565
  • 2015
Avicenna J
  • Phytomed. 2, 206
  • 2012
Hepatol
  • Res. 42, 181
  • 2012
...
1
2
...