Lubrication and wear properties of grafted polyelectrolytes, hyaluronan and hylan, measured in the surface forces apparatus.

@article{Benz2004LubricationAW,
  title={Lubrication and wear properties of grafted polyelectrolytes, hyaluronan and hylan, measured in the surface forces apparatus.},
  author={Marcel Benz and Nianhuan Chen and Jacob N Israelachvili},
  journal={Journal of biomedical materials research. Part A},
  year={2004},
  volume={71 1},
  pages={6-15}
}
Hyaluronan is believed to have an important function in the boundary biolubrication of articular cartilage. Using a Surface Forces Apparatus, we tested the tribological properties of surface bound, rather than "free" hyaluronan. The grafting process of the polyelectrolyte included either a biological route via an HA-binding protein or a chemical reaction to covalently bind the polymer to a lipid bilayer coated surface. In another reaction, we constructed a surface with covalently grafted hylan… CONTINUE READING