Lubeluzole in acute ischemic stroke. A double-blind, placebo-controlled phase II trial. Lubeluzole International Study Group.

@article{Diener1996LubeluzoleIA,
  title={Lubeluzole in acute ischemic stroke. A double-blind, placebo-controlled phase II trial. Lubeluzole International Study Group.},
  author={Hans-Christoph Diener and Werner Hacke and Michael Hennerici and J A R{\aa}dberg and L Hantson and Jacques de Keyser},
  journal={Stroke},
  year={1996},
  volume={27 1},
  pages={76-81}
}
BACKGROUND AND PURPOSE We aimed to assess the safety and efficacy of lubeluzole in patients with a clinical diagnosis of acute (< 6 hours) ischemic stroke in the carotid artery territory. METHODS A randomized, double-blind, placebo-controlled multicenter trial was conducted in 232 patients. Because treatment was administered within 6 hours and a CT scan was not mandatory before the start of treatment, 39 patients with either an intracerebral hemorrhage or ischemic stroke in the… CONTINUE READING
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