Lrrk2 p.Q1111H substitution and Parkinson's disease in Latin America.


Mutations in the LRRK2 gene are the most common genetic cause of Parkinson's disease, with frequencies displaying a high degree of population-specificity. Although more than 100 coding substitutions have been identified, only seven have been proven to be highly penetrant pathogenic mutations. Studies however are lacking in non-white populations. Recently… (More)
DOI: 10.1016/j.parkreldis.2011.05.003


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@article{Mata2011Lrrk2PS, title={Lrrk2 p.Q1111H substitution and Parkinson's disease in Latin America.}, author={Ignacio Mata and Greggory J Wilhoite and Dora Yearout and Justin A Bacon and Mario R Cornejo-Olivas and Pilar Mazzetti and Victoria Marca and Olimpio Ortega and Oscar Pastor Acosta and Carlos Cosentino and Lu{\'i}s Torres and {\'A}ngel C. Medina and Carolina Perez-Pastene and Fernando D{\'i}az-Grez and Carles Vilari{\~n}o-G{\"{u}ell and Pablo Venegas and Marcelo C. Miranda and Osvaldo Trujillo-Godoy and Luis Layson and Rodrigo Avello and Elena Di{\'e}guez and V{\'i}ctor Raggio and Federico Eduardo Micheli and Claudia Perandones and Victoria Pingarron Alvarez and Juan Segura-Aguilar and Matthew John Farrer and Cyrus P Zabetian and Owen A. Ross}, journal={Parkinsonism & related disorders}, year={2011}, volume={17 8}, pages={629-31} }