Lowering of interstitial fluid pressure after neurogenic inflammation is inhibited by mystixin-7 peptide.

@article{Gjerde2000LoweringOI,
  title={Lowering of interstitial fluid pressure after neurogenic inflammation is inhibited by mystixin-7 peptide.},
  author={E A Gjerde and Kathrine Woie and Edward T. Wei and Rolf K. Reed},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2000},
  volume={279 3},
  pages={H1377-82}
}
Soft tissue injury is accompanied by lowering of interstitial fluid pressure (P(if)), plasma protein extravasation, and edema. Inflammation was produced by electrical stimulation (ES) of the vagus and the effects of the synthetic peptide mystixin-7 (p-anisoyl-Arg-Lys-Leu-Leu-D-Thi-Ile-D-Leu-NH(2)) on P(if) were examined. Micropuncture measurement of P(if) in submucosa, without opening the trachea, was conducted on rats anesthetized with pentobarbital sodium (50 mg/kg) and euthanized with… CONTINUE READING
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