Lowering midlife levels of systolic blood pressure as a public health strategy to reduce late-life dementia: perspective from the Honolulu Heart Program/Honolulu Asia Aging Study.

@article{Launer2010LoweringML,
  title={Lowering midlife levels of systolic blood pressure as a public health strategy to reduce late-life dementia: perspective from the Honolulu Heart Program/Honolulu Asia Aging Study.},
  author={Lenore J. Launer and Timothy W. Hughes and Binbing Yu and Kamal H. Masaki and Helen Petrovitch and George Webster Ross and Lon R. White},
  journal={Hypertension},
  year={2010},
  volume={55 6},
  pages={
          1352-9
        }
}
To estimate the potential benefits of lowering systolic blood pressure (SBP) toward preventing late-life dementia, we estimated the population-attributable risk of elevated SBP for dementia. Analyses are based on the cohort of 8006 Japanese American men (born 1900-1919) followed since 1965 as a part of the Honolulu Heart Program, continued as the Honolulu Asia Aging Study. Midlife cardiovascular risk factors and late-life brain function are well described. We estimated the population… CONTINUE READING

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  • Table S1: Description of the sample by mid-life treatment status and age: HHP/HAAS Treated with antihypertensive meds Untreated Untreated Normotensive <50 yrs old: Reference Characteristic <50 yrs old ≥50 yrs old <50 yrs old* ≥50 yrs old (n=631) (n=2602) (n=688)
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