Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial.

@article{Green2007LoweringHW,
  title={Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial.},
  author={Timothy J Green and Jennifer A McMahon and Clark Murray Skeaff and Sheila M. Williams and Susan J Whiting},
  journal={The American journal of clinical nutrition},
  year={2007},
  volume={85 2},
  pages={460-4}
}
BACKGROUND In recent prospective studies, higher homocysteine concentrations were shown to be a risk factor for osteoporotic fractures in older persons. Supplements containing folate and vitamins B-12 and B-6 lower homocysteine concentrations. OBJECTIVE The objective of the study was to determine in healthy older persons whether lowering homocysteine with B vitamins affects plasma biomarkers of bone turnover. DESIGN Healthy older persons (n = 276; aged >or=65 y) were randomly assigned to… CONTINUE READING
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