Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. Homocysteine Lowering Trialists' Collaboration.

@article{TrialistsCollaboration1998LoweringBH,
  title={Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. Homocysteine Lowering Trialists' Collaboration.},
  author={Homocysteine Lowering Trialists’Collaboration},
  journal={BMJ},
  year={1998},
  volume={316 7135},
  pages={894-8}
}
  • Homocysteine Lowering Trialists’Collaboration
  • Published 1998 in BMJ
OBJECTIVE To determine the size of reduction in homocysteine concentrations produced by dietary supplementation with folic acid and with vitamins B-12 or B-6. DESIGN Meta-analysis of randomised controlled trials that assessed the effects of folic acid based supplements on blood homocysteine concentrations. Multivariate regression analysis was used to determine the effects on homocysteine concentrations of different doses of folic acid and of the addition of vitamin B-12 or B-6. SUBJECTS… CONTINUE READING
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