Lowered tissue-fluid oncotic pressure protects the blood volume in the nephrotic syndrome.

@article{Koomans1986LoweredTO,
  title={Lowered tissue-fluid oncotic pressure protects the blood volume in the nephrotic syndrome.},
  author={Hein A. Koomans and A B M Tom Geers and Evert J Dorhout Mees and Wouter Kortlandt},
  journal={Nephron},
  year={1986},
  volume={42 4},
  pages={317-22}
}
We have studied the role of adjustments of tissue-fluid colloid osmotic pressure (COP) in the maintenance of the blood volume in 10 patients with the nephrotic syndrome before and after diuretic treatment until dry weight. A mean weight reduction of 13.5 +/- 6.4 kg was attended by a fall in blood volume in 3 patients and no change in 6, but the final blood volume was within the normal range: 84.3 +/- 3.7 ml/kg (normal value: 87.6 +/- 8.8 ml/kg). Albumin content and COP of tissue-fluid, obtained… CONTINUE READING