Lower plasma CC16, a natural anti-inflammatory protein, and increased plasma interleukin-1 receptor antagonist in schizophrenia: effects of antipsychotic drugs.

@article{Maes1996LowerPC,
  title={Lower plasma CC16, a natural anti-inflammatory protein, and increased plasma interleukin-1 receptor antagonist in schizophrenia: effects of antipsychotic drugs.},
  author={Michael Maes and Eug{\`e}ne Bosmans and Rakesh Ranjan and Eric Vandoolaeghe and Herbert Y Meltzer and M De Ley and Ron Berghmans and G Stans and Roger Desnyder},
  journal={Schizophrenia research},
  year={1996},
  volume={21 1},
  pages={39-50}
}
Recently, it was suggested that in vivo activation of the monocytic and T-lymphocytic arms of cell-mediated immunity (CMI) may occur in schizophrenia and that antipsychotic drugs may modify CMI. The aim of the present study was to examine plasma soluble interleukin-2 receptor (sIL-2R), soluble suppressor/cytotoxic antigen (sCD8), interleukin-1 receptor antagonist (IL-1RA), and Clara cell protein (CC16) concentrations in normal controls, nonmedicated schizophrenic patients, and schizophrenic… CONTINUE READING

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