Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls.

@article{Misra2008LowerGH,
  title={Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls.},
  author={Madhusmita Misra and Miriam A. Bredella and Patrika M Tsai and Nara Mendes and Karen Klahr Miller and Anne Klibanski},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2008},
  volume={295 2},
  pages={E385-92}
}
Although body composition, insulin sensitivity, and lipids are markedly altered in overweight adolescents, hormonal associations with these parameters have not been well characterized. Growth hormone (GH) deficiency and hypercortisolemia predispose to abdominal adiposity and insulin resistance, and GH secretion is decreased in obese adults. We hypothesized that low-peak GH on the GH-releasing hormone (GHRH)-arginine stimulation test and high cortisol in overweight adolescents would be… CONTINUE READING