Lower cognitive reserve in the aging human immunodeficiency virus-infected brain.

@article{Chang2013LowerCR,
  title={Lower cognitive reserve in the aging human immunodeficiency virus-infected brain.},
  author={Linda Chang and John L. Holt and Renat Yakupov and C. S. Jiang and T. Ernst},
  journal={Neurobiology of aging},
  year={2013},
  volume={34 4},
  pages={1240-53}
}
More HIV-infected individuals are living longer; however, how their brain function is affected by aging is not well understood. One hundred twenty-two men (56 seronegative control [SN] subjects, 37 HIV subjects with normal cognition [HIV+NC], 29 with HIV-associated neurocognitive disorder [HAND]) performed neuropsychological tests and had acceptable functional magnetic resonance imaging scans at 3 Tesla during tasks with increasing attentional load. With older age, SN and HIV+NC subjects showed… CONTINUE READING

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