Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures.

@article{Ruvolo2007LowerAR,
  title={Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures.},
  author={G. Ruvolo and L. Bosco and A. Pane and Giovanni Morici and E. Cittadini and M. Roccheri},
  journal={Fertility and sterility},
  year={2007},
  volume={87 3},
  pages={
          542-6
        }
}
  • G. Ruvolo, L. Bosco, +3 authors M. Roccheri
  • Published 2007
  • Medicine
  • Fertility and sterility
  • OBJECTIVE To investigate the effects of recombinant (r-) LH supplementation in "low responder" patients undergoing ovarian stimulation with r-FSH for an IVF program. The apoptosis rate in cumulus cells was used as an indicator of oocyte quality. DESIGN Comparison of the rate of DNA fragmentation and caspase-3 activity in cumulus cells in women stimulated with r-LH and r-FSH, versus patients treated with r-FSH alone (control). SETTING In vitro fertilization (IVF) laboratory. PATIENT(S… CONTINUE READING

    Paper Mentions

    OBSERVATIONAL CLINICAL TRIAL
    HP-hMG, recombinant FSH (r-hFSH) and a combination of r-hFSH/r-hLH, are commonly used for ovarian stimulation in infertile women undergoing IVF/ICSI treatments. Several publications… Expand
    ConditionsInfertility
    The use of androgens or androgen-modulating agents in poor responders undergoing in vitro fertilization: a systematic review and meta-analysis.
    • 96
    • Highly Influenced
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