Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures.

@article{Ruvolo2007LowerAR,
  title={Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures.},
  author={Giovanni Ruvolo and Liana Bosco and Antonina Pane and Giovanni Morici and Ettore Cittadini and Maria Carmela Roccheri},
  journal={Fertility and sterility},
  year={2007},
  volume={87 3},
  pages={
          542-6
        }
}
OBJECTIVE To investigate the effects of recombinant (r-) LH supplementation in "low responder" patients undergoing ovarian stimulation with r-FSH for an IVF program. The apoptosis rate in cumulus cells was used as an indicator of oocyte quality. DESIGN Comparison of the rate of DNA fragmentation and caspase-3 activity in cumulus cells in women stimulated with r-LH and r-FSH, versus patients treated with r-FSH alone (control). SETTING In vitro fertilization (IVF) laboratory. PATIENT(S… CONTINUE READING
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Gene Expression and Apoptosis Levels in Cumulus Cells of Patients with Polymorphisms of FSHR and LHB Undergoing in Vitro Fertilization Program.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2017

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The mammalian oocyte orchestrates the rate of ovarian follicular development.

Proceedings of the National Academy of Sciences of the United States of America • 2002