Low-temperature carbon utilization is regulated by novel gene activity in the heart of a hibernating mammal.

@article{Andrews1998LowtemperatureCU,
  title={Low-temperature carbon utilization is regulated by novel gene activity in the heart of a hibernating mammal.},
  author={Matthew T Andrews and Teresa L. Squire and Chris Bowen and M B Rollins},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 14},
  pages={8392-7}
}
Hibernation is a physiological adaptation characterized by dramatic decreases in heart rate, body temperature, and metabolism, resulting in long-term dormancy. Hibernating mammals survive for periods up to 6 mo in the absence of food by minimizing carbohydrate catabolism and using triglyceride stores as their primary source of fuel. The cellular and molecular mechanisms underlying the changes from a state of activity to the hibernating state are poorly understood; however, the selective… CONTINUE READING
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