Low serum vitamin B12 is common in coeliac disease and is not due to autoimmune gastritis

@article{Dickey2002LowSV,
  title={Low serum vitamin B12 is common in coeliac disease and is not due to autoimmune gastritis},
  author={William Dickey},
  journal={European Journal of Gastroenterology \& Hepatology},
  year={2002},
  volume={14},
  pages={425-427}
}
  • W. Dickey
  • Published 1 April 2002
  • Medicine
  • European Journal of Gastroenterology & Hepatology
Objective Although coeliac disease is a disorder of the proximal small bowel, associated vitamin B12 deficiency has been reported. This study aimed to assess the prevalence of B12 deficiency in a large series of coeliac patients, and to exclude the possibility that it is due to associated autoimmune gastritis. Design Prospective routine measurement of serum B12 in coeliac patients, with investigations for pernicious anaemia/autoimmune gastritis in B12-deficient patients. Setting… 
THE ASSOCIATION OF VITAMIN D DEFICIENCY AND ANEMIA WITH CELIAC DISEASE IN A YOUNG CHILD: A CASE STUDY
Celiac disease (CD) is an autoimmune disease triggered by the ingestion of foods containing gluten (gliadin), which is associated with vitamin D deficiency and with a number of hematological
Complementary Serologic Investigations in Children with Celiac Disease Is Unnecessary during Follow-Up.
TLDR
Complementary blood investigations are relevant at the time of diagnosis of CD but have little diagnostic yield during follow-up visits once the patient is placed on a gluten-free diet, so it is recommended that these variables only be assessed on indication, such as fatigue or abnormal growth.
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TLDR
Reducing the risk of homocysteine-related disease may be another reason for aggressive diagnosis and treatment of CD, and gluten exclusion in CD improves folate status and normalizes homocrysteine concentrations.
Vitamin and Mineral Deficiencies Are Highly Prevalent in Newly Diagnosed Celiac Disease Patients
TLDR
Vitamin/mineral deficiencies are still common in newly “early diagnosed” untreated adult CD-patients, even though the prevalence of obesity at initial diagnosis is rising and vitamin deficiencies were barely seen in healthy controls.
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TLDR
On multivariate logistic regression, age, duration of symptoms, and presence of diarrhea were found to be the predictors of CD, and screening for CD should be included in the work up of otherwise unexplained nutritional anemia.
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TLDR
Micronutrient deficiencies remain common in adults with CD despite increased nonclassic presentation, and this study provides support for micronutrients assessment at the time of CD diagnosis.
Polyautoimmunity in autoimmune gastritis.
TLDR
Patients with autoimmune gastritis should be investigated for the presence of an autoimmune disease, in particular patients with enterochromaffin cell hyperplasia and those with serum gastrin and chromogranin A levels above cut-off values.
Anemia in celiac disease is multifactorial in etiology
TLDR
Assessing hematologic parameters from a cohort of patients seen at a tertiary care center for CD found inflammation appears to contribute as evidenced by the presence of anemia of chronic disease in some individuals.
Prevalence of hyperhomocysteinemia in adult gluten-sensitive enteropathy at diagnosis: role of B12, folate, and genetics.
  • S. Saibeni, A. Lecchi, +6 authors M. Vecchi
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2005
TLDR
Hyperhomocysteinemia is frequent in newly diagnosed GSE patients and might contribute to the occurrence of common complications of undiagnosed GSE, according to a prospective study performed in a tertiary care setting.
Screening Detected Celiac Disease in Children
TLDR
The correlation between the degree of enteropathy and the level of the serological markers (tTG-IgA) was investigated, and the effect and accuracy in each step of the diagnostic process to obtain CD diagnosis was investigated.
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