Low serum leptin predicts mortality in patients with chronic kidney disease stage 5.

@article{Scholze2007LowSL,
  title={Low serum leptin predicts mortality in patients with chronic kidney disease stage 5.},
  author={Alexandra Scholze and Dirk Rattensperger and Walter Zidek and Martin Tepel},
  journal={Obesity},
  year={2007},
  volume={15 6},
  pages={1617-22}
}
OBJECTIVE Leptin, secreted from adipose tissue, regulates food intake, energy expenditure, and immune function. It is unknown whether leptin predicts mortality in patients with chronic kidney disease stage 5 on hemodialysis therapy. RESEARCH METHODS AND PROCEDURES We performed a prospective cohort study of 71 patients with chronic kidney disease stage 5 in an outpatient hemodialysis center. Subjects were recruited in June 1998 and followed for 83 months. Survival was compared by the Kaplan… CONTINUE READING

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