Low serum bilirubin levels are independently and inversely related to impaired flow-mediated vasodilation and increased carotid intima-media thickness in both men and women.

@article{Erdoan2006LowSB,
  title={Low serum bilirubin levels are independently and inversely related to impaired flow-mediated vasodilation and increased carotid intima-media thickness in both men and women.},
  author={Doğan Erdoğan and H Ibrahim Gullu and Erkan Yildirim and D. K. Siong Tok and Ismail Kirbaş and Ozg{\"u}r Çiftçi and Semra Topcu Baycan and Haldun Muderrisoğlu},
  journal={Atherosclerosis},
  year={2006},
  volume={184 2},
  pages={431-7}
}
BACKGROUND Elevated levels of low-density lipoprotein (LDL) cholesterol and its oxidative modification have been described to be involved in the process of atherogenesis. Bilirubin, an antioxidant, prevents oxidative modification of LDL and therefore may protect from atherosclerosis and coronary heart disease (CHD). Impaired brachial artery flow-mediated dilatation (FMD), which means endothelial dysfunction (ED) and carotid intima-media thickness (IMT) are predictors for the development and… CONTINUE READING

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