Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes.

@article{Jimerson1992LowSA,
  title={Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes.},
  author={David C. Jimerson and Michael D. Lesem and Walter H. Kaye and Timothy D. Brewerton},
  journal={Archives of general psychiatry},
  year={1992},
  volume={49 2},
  pages={132-8}
}
Cerebrospinal fluid neurotransmitter metabolite levels were studied to assess whether measures of central serotonin, dopamine, or norepinephrine function are associated with severity of abnormal eating patterns in patients with bulimia nervosa. In comparison with healthy controls (N = 17), hospitalized bulimic patients with a history of binge eating more frequently than twice daily (N = 11) had significantly lower CSF concentrations of 5-hydroxyindoleacetic acid and homovanillic acid. For the… CONTINUE READING
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